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I ran into the same problem. There are troubleshooting options in the channel settings windows in FL Studio. The only way I was able to get the correct tone (the same that I get in Reaper with Bias) is to select the "Use Fixed Sized Buffers" option in the processing tab.


This could be a hardware driver problem. Do you have up to date drivers from your hardware. Also look at updating your video drivers as they can sometimes have an effect on your sound (as strange as that sounds).

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