Every little thing can affect the way a guitar sounds and plays. If you are an experimenter you might choose to remove the stickers and discern for yourself the effect it has on the sound and playability. Removing the stickers may also affect the vintage collectability of the instrument in the future. In fact any alterations to the instrument may affect future collectability if that is of concern to you. An individual instrument has it'sits own sound partially because of the way it's built and affected by the way it is played. If you like the way it sounds when you play it, keep it the way it is. If not, you may choose to make alterations. Personally, I subscribe to the old saying, "if it ain't broke don't fix it", but others may recommend differently.