You could always have a custom guitar built, or modify an existing guitar: Have the fretboard replaced and have the frets set to match the spacing on a Setar. But then the guitar would not be usable as a standard guitar.
In order to allow for different intonations, some innovators (like Tolgahan Çoğulu in the video below) have devised ways to make movable frets on a guitar. In the first one, individual partial-width frets move in slots for adjustment:
As you probably know, there are instruments from other traditions with movable frets (e.g. Sitar, Bağlama). The methods used on those instruments could also be adapted to a guitar-like instrument.
You may also notice in the description area of the above video, links to some other approaches:
- AUTOMATIC Microtonal Guitar, a one-string prototype with motorized frets controlled by computer to change to preset intonations:
- LEGO Microtonal Guitar, with a 3D-printed fingerboard base made to accept Lego pieces:
In case the video links go dead, here are some still photos of the inventor (and his son Atlas) with the three kinds of microtonal guitar:
Movable and Lego: