My two front teeth aren't the same height. One of them extends lower than the other by about 2mm. I've noticed recently that my mouthpiece patch on my clarinet mouthpiece shows two marks (from my teeth) way off center. However, If I try to correct this, only one of my teeth is actually touching the mouthpiece which makes it really uncomfortable. Should I worry about my teeth not being centered on my mouthpiece? If so, how can I mitigate this problem?
I dunno why you use a patch but that's more or less beside the point. My teeth are uneven as well; my correction was to let the mouthpiece "settle" into my embouchure. The most comfortable position was with the mouthpiece offset in my mouth by a millimeter or so -- which means I (or you) have to take care to keep the pressure on the reed side even across the reed.
If you have money :-), an oral surgeon will happily grind your incisors to an even level. I know - I asked one once.