The real instrument will sound more real, but as you note, there are many challenges to recording acoustic instruments or anything with a microphone that are completely bypassed when using a virtual instrument plugin.
With a plugin, you don't have to have an audio interface, microphone or cables. You don't have to have an actual acoustic instrument, which usually cost much more than a good plugin, DAW, computer, and controller combined. You don't have to make sure the plugin is in tune. You don't have to have a quiet room with good acoustics to record in.
So in all ways except sound quality, plugins are much easier to work with. These days plugins sound very good. They still don't sound exactly the same, but the convenience and cost savings that they offer makes them a very popular tradeoff.
Regarding editing, in my experience it's about the same. Editing an audio recording of a plugin is about the same difficulty as editing audio of an acoustic instrument. Editing the MIDI that is fed into a plugin can be easier than editing audio, but it has its own quirks.
Note that there are services online where you can send you MIDI tracks to and they will record the actual acoustic instruments for you in quality studios with quality equipment. The costs vary, but if you really want the acoustic sound and don't want to have to figure all of that out for yourself, you can pay to have a track recorded "for real".