One of the most annoying idiosyncrasies of standard guitar tuning EADGBE is that third between the G and the B. When you move chord shapes or scale patterns around the neck you always have to take account that G-B is a third instead of a fourth like the other strings.
I don't think it's a good idea to tune the guitar entirely in fourths as is suggested in Is even-interval tuning a sensible idea for lead guitar? This question is not a duplicate also because I am interested in the historical reasons for the EADGBE tuning as discussed in Why is the guitar tuned like it is?
I don't think tuning in fourths is good both for ergonomic reasons and for open string reasons but I think that shifting the third from GB to CE in a EADGCE tuning takes advantage of the symmetry of the low E and high E strings. Chord shapes across the neck are also identically shaped for one more precious string.
Why isn't the guitar tuned EADGCE? Is there an ergonomic reason or is it just historical, like QWERTY instead of Dvorak keyboards?