Probably not.
The line on necks like this is that thinner and flatter necks are "faster". I don't know about that, but with rounder fretboards, you can send to "fret out" on more extreme bends. There are compound radius necks which have flatter radii higher up the fretboard where you're more likely to bend.
Personally, I like a hard V neck like 5os Telecasters, but the brands that make these necks our them on instruments meant for shred, where ergonomics make for more notes per second, so it shouldn't make things harder
If possible, play the new instrument first to be sure of how it feels in the hand, but it should feel fine.